Which ARV is good for pregnancy?

Which ARV is good for pregnancy?

The antiretroviral drugs dolutegravir and emtricitabine/tenofovir alafenamide fumarate (DTG+FTC/TAF) may comprise the safest and most effective HIV treatment regimen currently available during pregnancy, researchers announced today.

Is TLD safe in early pregnancy?

Exposure to dolutegravir at the time of conception or during the first three months of pregnancy is associated with a small increased risk of neural tube defects, longer-term follow-up of a national birth cohort in Botswana has found.

Can HIV treatment with antiretroviral therapy be taken during pregnancy?

Should women with HIV take HIV medicines during pregnancy? Yes. All pregnant women with HIV should take HIV medicines throughout pregnancy for their own health and to prevent perinatal transmission of HIV. (HIV medicines are called antiretrovirals.)

Which ARV should be avoided during pregnancy?

Cobicistat-boosted ARV drugs (ATV, DRV, or EVG) are Not Recommended for use in pregnancy. As noted above, EVG, DRV, ATV, and COBI levels have been found to be significantly lower during the third trimester than during the postpartum period.

What are the side effects of Arvs during pregnancy?

Most side effects are minor and include nausea, feeling tired and diarrhoea. Sometimes, but more rarely, they can be very serious. Some effects of HIV medicines are very similar to the changes that happen during pregnancy, eg morning sickness and the nausea caused by ART.

Is the use of dolutegravir safe for pregnant woman?

Dolutegravir (DTG) appears to be safe if started in pregnancy; however, there are concerns of preconception safety signal.

What are the side effects of TLD?

WHAT DOES TLD LOOK LIKE? WHAT ARE THE SIDE EFFECTS? Side effects are uncommon. Some patients have reported nausea, insomnia or occasional dizziness, but these are mild and manageable.

Is DTG safe in pregnancy?

Based on new evidence assessing benefits and risks, the WHO recommends the use of the HIV drug dolutegravir (DTG) as the preferred first-line and second-line treatment for all populations, including pregnant women and those of childbearing potential.

Can efavirenz be used in pregnancy?

Efavirenz-based triple regimens, initiated after the first trimester of pregnancy and discontinued after childbirth, are potentially an important alternative for reducing mother-to-child transmission in pregnant women who do not yet require antiretroviral treatment.