What is the difference between parietal cells and chief cells?
What is the difference between parietal cells and chief cells?
The two main types of exocrine secretory cells of the stomach are parietal cells and chief cells. Parietal cells secrete hydrochloric acid and chief cells secrete digestive enzymes such as pepsin. These cells secrete their products when activated by signals from the body such as hormones and neurotransmitters.
What is the relationship between parietal cells and chief cells?
Explanation: The stomach contains several cell types, each with a specific mechanism of action. Chief cells produce pepsinogen, which is converted to pepsin by hydrochloric acid in the stomach. Parietal cells produce hydrochloric acid, allowing this conversion.
Which histological structure contain chief and parietal cells?
stomach wall
Histologically, most of the stomach wall contains gastric glands (or fundic glands). These consist primarily of parietal cells and chief cells.
What is a chief cell do?
Chief cells are responsible for secreting pepsinogen. They have basally located nuclei and a basophilic cytoplasm with abundant rough endoplasmic reticulum and many secretory granules that contain pepsinogen. These are secreted into the lumen of the gastric gland.
What is the relationship between the stomach the gastric glands The parietal cells and the chief cells?
Explanation: Parietal cells are the epithelial cells that secrete HCl and intrinsic factor. They are located in the gastric glands found in lining of fundus and stomach. The gastric chief cells , are cells in the stomach that release pepsinogen and chymosin.
How do parietal cells and chief cells work together to break down protein in the stomach?
Pepsin Pearls Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin.
Where are parietal cells found?
the stomach
Parietal cells are present in glands within the fundus and body of the stomach and are the largest cells in these glands. They originate from immature progenitor cells in the gland isthmus and then migrate upward toward the pit region and downward toward the base of the gland.
What do parietal cells do?
Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food, absorption of minerals, and control of harmful bacteria.
What is composed of chief cells?
Histology. Gastric chief cells are epithelial cells which are found within the gastric unit or gastric gland, and form the base of the gastric unit. The gastric chief cell has an extensive network of lamellar rough endoplasmic reticulum organized around the nucleus.
What is parietal cells?
Parietal cells are specialized cells in the stomach that make acid to help in food digestion and also make intrinsic factor. Intrinsic factor is required for the absorption of vitamin B12 from food.