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What is Paucibacillary and Multibacillary?

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What is Paucibacillary and Multibacillary?

Paucibacillary patients are those who are skin smear negative and show no evidence of more advanced disease on biopsy. Multibacillary patients are those who are skin smear positive and/or have a biopsy indicating more advanced disease.

What are the 3 types of leprosy?

The first system recognizes three types of Hansen’s disease: tuberculoid, lepromatous, and borderline. A person’s immune response to the disease determines which of these types of Hansen’s disease they have: In tuberculoid Hansen’s disease, the immune response is good.

What are the 4 types of leprosy?

Leprosy

  • Borderline Lepromatous Leprosy.
  • Borderline Tuberculoid Leprosy.
  • Indeterminate Leprosy.
  • Lepromatous Leprosy.
  • Midborderline Leprosy.
  • Tuberculoid Leprosy.

Who Multibacillary leprosy treatment?

For the treatment of patients with multibacillary leprosy, WHO recommends a combination of rifampicin, clofazimine and dapsone; for patients with paucibacillary leprosy, MDT uses a combination of rifampicin and dapsone.

What is Multibacillary?

Multibacillary (MB), or lepromatous, Hansen’s disease is characterized by generalized or diffuse involvement of the skin, a thickening of the peripheral nerves under microscopic examination, and has the potential to involve other organs, the eyes, nose, testes, and bone.

What does Multibacillary mean?

[mul″tĭ-bas´ĭla-re] having numerous bacilli; see leprosy.

What is Paucibacillary and Multibacillary leprosy?

Paucibacillary leprosy: 2 to 5 patches or lesions on the skin. Multibacillary leprosy: >5 patches or lesions on the skin. Recommended types of surveillance. Individual patient records at peripheral level for investigation and case-management.

What are the 3 main symptoms of leprosy?

The three main symptoms of leprosy include:

  • Skin patches which may be red or have a loss of pigmentation.
  • Skin patches with diminished or absent sensations.
  • Numbness or tingling in your hands, feet, arms and legs.
  • Painless wounds or burns on the hands and feet.
  • Muscle weakness.

Why clofazimine is used in Multibacillary leprosy?

Because all MDT regimens for MB leprosy contain clofazimine, which has significant anti-inflammatory activity, severe ENL is encountered less frequently today. In milder forms of ENL, therapy may require only mild analgesics.

What are anti Leprotic drugs?

The drugs used in WHO-MDT are a combination of rifampicin, clofazimine and dapsonefor MB leprosy patients and rifampicin and dapsone for PB leprosy patients. Among these drugs, rifampicin is the most important anti-leprosy drug and therefore, is included in the treatment of both types of leprosy.

Who Multibacillary leprosy classification?

In the classification based on skin smears, patients showing negative smears at all sites are said to have paucibacillary leprosy (PB), while those showing positive smears at any site are said to have multibacillary leprosy (MB).

What is tuberculoid leprosy?

Tuberculoid. A mild, less severe form of leprosy. People with this type have only one or a few patches of flat, pale-colored skin (paucibacillary leprosy). The affected area of skin may feel numb because of nerve damage underneath. Tuberculoid leprosy is less contagious than other forms.