What is Ki67 breast cancer?

What is Ki67 breast cancer?

Ki67 is a nuclear antigen that is an excellent marker of active cell proliferation in the normal and tumor cell populations (1). It has been proposed as a useful clinical marker for breast cancer subtype classification, prognosis, and prediction of therapeutic response (2–4).

What does ER PR HER2 mean?

ER = estrogen receptor, Her2 = human epidermal growth factor receptor 2, PR = progesterone receptor, + = positive, − = negative.

What is cancer lifestyle factor?

The important lifestyle factors that affect the incidence and mortality of cancer include tobacco, alcohol, diet, obesity, infectious agents, environmental pollutants, and radiation.

How do I deal with being told I have cancer?

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• Keep the lines of communication open. Maintain honest, two-way communication with your loved ones, doctors and others after your cancer diagnosis.
• Maintain a healthy lifestyle. This can improve your energy level.
• Let friends and family help you.
• Review your goals and priorities.
• Fight stigmas.

What is normal Ki-67?

The median value for Ki67 was 15% (range: <1% – 98%), which was used to define low or high Ki-67 expression levels: Ki-67 values <15% were defined as “low Ki-67”, whereas values ≥ 15% were defined as “high Ki-67”.

Is it better to have HER2-positive or HER2-negative?

Breast cancer cells with higher than normal levels of HER2 are called HER2-positive. These cancers tend to grow and spread faster than breast cancers that are HER2-negative, but are much more likely to respond to treatment with drugs that target the HER2 protein.

Is it better to be ER PR positive or negative?

Tumors that are ER/PR-positive are much more likely to respond to hormone therapy than tumors that are ER/PR-negative. You may have hormone therapy after surgery, chemotherapy, and radiation are finished. These treatments can help prevent a return of the disease by blocking the effects of estrogen.

What is a risk factor for cancer?

The most common risk factors for cancer include aging, tobacco, sun exposure, radiation exposure, chemicals, and other substances, some viruses and bacteria, certain hormones, family history of cancer, alcohol, poor diet, lack of physical activity, or being overweight.

What does cancer fatigue feel like?

People who experience cancer fatigue often describe it as “paralyzing.” Usually, it comes on suddenly and is not the result of activity or exertion. With this type of fatigue, no amount of rest or sleep helps. You feel physically, emotionally and mentally exhausted most of the time.

What is considered a high Ki67 score?

Understanding Your Ki-67 Results Less than 10% is considered low. 20% or higher is considered high.