What is included in von Willebrand panel?

What is included in von Willebrand panel?

Von Willebrand factor testing includes VWF antigen, which measures the amount of VWF, and VWF activity (also known as Ristocetin Cofactor), which evaluates the function of VWF. Some laboratories may offer a panel that includes both of these tests along with a factor VIII activity test.

What is a normal von Willebrand factor?

In the general population, the mean level of plasma VWF is 100 IU per dL, with a normal reference range between 50 and 200 IU per dL.

What does an elevated von Willebrand factor mean?

VWF is an acute-phase reactant and may be elevated above baseline in association with a variety of conditions including inflammation, stress, exercise, liver disease, pregnancy, or estrogen therapy. Baseline VWF levels also increase with aging.

What does a low von Willebrand factor mean?

Overview. Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn’t clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn’t perform as it should.

Is D dimer elevated in von Willebrand disease?

Most significant is that patients need to be treated early in the disease progression, when high levels of VWF, P-selectin and fibrinogen are present, with normal or slightly increased levels of D-dimer (however, D-dimer levels will rapidly increase as the disease progresses).

How is von Willebrand disease diagnosed?

To evaluate you for von Willebrand disease, your doctor will likely ask you detailed questions about your medical history and check for bruises or other signs of recent bleeding. Your doctor will also likely recommend the following blood tests: Von Willebrand factor antigen.

How do you diagnose von Willebrand’s disease?

Can von Willebrand disease cause fatigue?

Blood clots greater than 1 inch (2.5 centimeters) in diameter in your menstrual flow. The need to change your menstrual pad or tampon more than once an hour. The need to use double sanitary protection for menstrual flow. Symptoms of anemia, including tiredness, fatigue or shortness of breath.

Does von Willebrand make you tired?

The weakening, fatigue and other disruptive effects of VWD can be stopped. Even childbirth can be made safe for a mother and baby. If you have unexplained bleeding symptoms, remember to ask your doctor, “Could I have von Willebrand disease?”