What is adenosine 6mg 2ml?
What is adenosine 6mg 2ml?
Adenosine injection slows conduction time through the A-V node, can interrupt the reentry pathways through the A-V node, and can restore normal sinus rhythm in patients with paroxysmal supraventricular tachycardia (PSVT), including PSVT associated with Wolff-Parkinson-White Syndrome.
What is adenosine used for?
Adenosine has uses as both a diagnostic or therapeutic agent. As a diagnostic agent, adenosine can be utilized in myocardial perfusion stress imaging due to its vasodilatory effects. As a therapeutic agent, adenosine can be used due to its antiarrhythmic properties in supraventricular tachycardia (SVT).
How many ml is adenosine?
Each vial contains 6mg of adenosine per 2ml (3mg/ml). For a full list of excipients, see Section 6.1.
How much adenosine do you give?
Initial dose: 6 mg given as a rapid intravenous bolus (administered over a 1-2 second period). Repeat administration: If the first dose does not result in elimination of the supraventricular tachycardia within 1-2 minutes, 12 mg should be given as a rapid intravenous bolus.
When do you give adenosine for SVT?
When vagal maneuvers fail to terminate stable narrow-complex SVT, the primary medication of choice is adenosine. For the unstable patient with a regular and narrow QRS complex, adenosine may also be considered prior to synchronized cardioversion.
How does adenosine slow heart rate?
Adenosine re- leased from working myocardium acts to increase oxygen supply by causing coronary vasodilation, and to decrease oxygen consumption by slowing heart rate and attenuating the excitatory effects of P-adrenergic stimulation (Fig. 1). Thus, adenosine acts as a nega- tive feedback modulator of cardiac work.
What does adenosine do to heart?
Adenosine is known to regulate myocardial and coronary circulatory functions. Adenosine not only dilates coronary vessels, but attenuates beta-adrenergic receptor-mediated increases in myocardial contractility and depresses both sinoatrial and atrioventricular node activities.
Why do doctors use adenosine?
ADENOSINE (a DEN uh seen) is used to bring your heart back into a normal rhythm. This medicine is not useful for all types of irregular heart beats. It may be used to test the heart for coronary artery disease.
How do you prepare adenosine infusion?
- Adenosine Infusion should be administered undiluted as a continuous peripheral intravenous infusion at a dose of 140 µg/kg/min for six minutes using an infusion pump.
- After three minutes of Adenosine Infusion, the radionuclide is injected to ensure sufficient time for peak coronary blood flow to occur.
Should adenosine be diluted?
There has been provider concern that diluting adenosine prior to administration could reduce the drug’s efficacy. Our results counter this argument and show that the SS method is highly effective with a 73% chance of successful NSR conversion with first dose of adenosine and 100% chance with repeat doses.