What are the serotypes of pneumococcal?
What are the serotypes of pneumococcal?
The serotypes are: 1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19A, 19F, 20, 22F, 23F, and 33F.
How many serotypes of Streptococcus pneumoniae are there?
There are more than 100 distinct serotypes of Streptococcus pneumoniae. The pneumococcal capsule serves as the target for current highly effective multivalent vaccines against this global pathogen.
What is Streptococcus pneumoniae IgG?
Streptococcus pneumoniae is a gram-positive bacteria that causes a variety of infectious diseases in children and adults. More than 90 serotypes of Streptococcus pneumoniae have been identified, based on cell wall polysaccharides.
What serotypes are in Pneumovax?
PNEUMOVAX® 23 is a vaccine indicated for active immunization for the prevention of pneumococcal disease caused by the 23 serotypes contained in the vaccine (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, Page 3 2 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F).
What are the 13 strains of pneumococcal pneumonia?
Types and Composition of Pneumococcal Vaccines PCV13 (Prevnar13®) includes purified capsular polysaccharide of 13 serotypes of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 18C, and 23F) conjugated to a nontoxic variant of diphtheria toxin known as CRM197.
What are normal range for pneumococcal antibodies?
The geometrical mean titre of pneumococcal IgG levels was determined from a healthy UK adult population by the current clinical assay [10] with a level of >640 µg/ml being regarded as ‘normal’ and ≥50 µg/ml being regarded as positive.
What determines the different serotypes of Streptococcus?
Each serotype is distinguished based on the chemical composition of and antigenic differences in the capsular polysaccharide. Global surveillance has shown that only a limited number of capsular serotypes cause more than 70–80% of IPD.
What serotype is Prevnar 13?
PCV13 (Prevnar13®) includes purified capsular polysaccharide of 13 serotypes of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 18C, and 23F) conjugated to a nontoxic variant of diphtheria toxin known as CRM197.
What is the difference between Prevnar 20 and Prevnar 23?
Prevnar 20 is currently approved for use in adults at least 18 years old, but official CDC recommendations haven’t been established yet. It’s given as a single-dose injection into the muscle. Pneumovax 23 is approved for use in children 2 years and older at higher risk of infection and adults at least 50 years old.
Should I get Prevnar 13 or Pneumovax 23?
CDC recommends pneumococcal vaccination for young children, older adults, and certain other people. All children younger than 2 years old should receive PCV13. Children 2 through 18 years old with certain medical conditions should receive PCV13 and PPSV23. If PCV15 is used, it should be followed by a dose of PPSV23.
What is a serotype of a virus?
Serotypes are groups within a single species of microorganisms, such as bacteria or viruses, which share distinctive surface structures.