How long does tisseel take to thaw?

How long does tisseel take to thaw?

The total thawing and warming time cannot exceed 48 hours. TISSEEL Kit (Freeze-Dried) Apply TISSEEL using the DUPLOJECT Fibrin Sealant Preparation and Application System or an equivalent delivery system (including open and minimally invasive spray devices) cleared by FDA for use with TISSEEL.

How do you thaw tisseel?

Using sterile technique, transfer the sterile inner pouch and contents onto the sterile field. Tisseel in the PRIMA syringe may be thawed AND warmed using one of the following methods: 1. Rapid thawing/warming (sterile water bath) – Recommended method 2. Thawing/warming in a non-sterile water bath 3.

Is tisseel frozen?

Dosage Forms and Strengths TISSEEL Pre-Filled Syringe (Frozen) is supplied as 2 mL, 4 mL and 10 mL (total volume) pack sizes with the DUO Set (AST Syringe) or DUPLOJECT COMBI (PRIMA Syringe).

How long does it take for tisseel to set?

Instructions:

Is tisseel human tissue?

TISSEEL is made from human plasma. Because this product is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses, the variant Creutzfeldt-Jakob disease (vCJD) agent and, theoretically the Creutzfeldt-Jakob disease (CJD) agent.

How long does fibrin glue last?

Biodegradation of this fibrin sealant occurs over 30 days [65]. The effectiveness of this product has been demonstrated in a multicenter, prospective, randomized trial [65, 70] including cardiac, hepatic [71], general surgical, and orthopedic patients (cancellous bone bleeding) [72].

How long is Vistaseal good for once thawed?

After thawing, the kit containing the VISTASEAL syringe holder with pre-filled syringes and Dual Applicator can be stored before use for not more than 48 hours in the refrigerator at 2 ‑ 8 ºC [36 – 46 ºF] or 24 hours at room temperature (20 – 25 °C [68 – 77 ºF]) if it remains sealed in the original packaging.

What is tisseel made from?

Is tisseel fibrin glue?

Tisseel Fibrin Sealant (fibrinogen human, human thrombin kit) is a fibrin sealant used as an adjunct to hemostasis in adult and pediatric patients (older than 1 month of age) undergoing surgery when control of bleeding by conventional surgical techniques (such as suture, ligature, and cautery) is ineffective or …

What is tisseel used for in surgery?

Indications. Hemostasis: Tisseel is a fibrin sealant indicated for use as an adjunct to hemostasis in adult and pediatric patients (>1 month of age) undergoing surgery when control of bleeding by conventional surgical techniques (such as suture, ligature, and cautery) is ineffective or impractical.

Is tisseel a blood product?

Does fibrin glue contain blood?

Fibrin sealant topical is made from human plasma (part of the blood) which may contain viruses and other infectious agents.