How can CMT be treated?
How can CMT be treated?
There is no cure for CMT, but physical and occupational therapies, braces and other orthopedic devices, and orthopedic surgery can help people cope with the disabling symptoms of the disease. In addition, pain-relief drugs can be prescribed for individuals who have severe nerve pain.
What causes CMT1A?
CMT1A is caused by having an extra copy (a duplication) of the PMP22 gene. It is inherited in an autosomal dominant manner.
What vitamins are good for CMT?
Vitamin C has been proposed as a treatment for CMT, because vitamin C is necessary for myelination (development of the myelin, or insulation around the nerve fibres) in laboratory cultures of nerve cells and the peripheral nerves of mice.
How quickly does CMT progress?
In children with CMT, electrophysiological changes can be detected as early as 2 years of age, with abnormally small CMAPs and progressively worsening NCV until approximately 6 years of age when it stabilizes.
Is gabapentin good for CMT?
Medication Summary Musculoskeletal pain may respond to acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs). Neuropathic pain may respond to tricyclic antidepressants or antiepileptic drugs, such as carbamazepine or gabapentin.
What medications make CMT worse?
There are some medications that are potentially toxic to CMT patients. The following medications are considered to be high risk: Vinca alkaloids (Vincristine), Taxols (paclitaxel, docetaxel, cabazitaxel).
Can CMT1A be mild?
Overall, as noted in this study, a sub-normal sprinting ability is consistent with a mild symptom of CMT1A.
How rare is CMT1A?
CMT1C. CMT1C is rare, affecting less than 1% of all cases. It is caused by mutations in the LITAF gene, which is situated on chromosome 16. It encodes a protein with the same name, which has a critical role in peripheral nerves function.
What does CMT pain feel like?
Because CMT causes damage to sensory nerve fibers (axons), people with CMT can feel tingling and burning sensations in the hands and feet, usually causing only mild discomfort but sometimes causing pain. The sense of touch is diminished, as is the ability to sense changes in temperature.
Does CMT affect memory?
The most common cause of CMT is the duplication of a region on the short arm of chromosome 17, which includes the gene PMP22. We report a thirty-seven-year-old man with CMT disease having sleep, memory and attention disorders characterized by brief retrograde amnesia at early age.
Are there any new treatments for CMT?
There’s some promising research that may provide new ways of treating people with CMT. This research includes: using stem cells (cells at an early stage of development) to repair nerve damage. using hormones (powerful chemicals) and gene therapy to slow the progression of the condition.
How do you strengthen your legs with CMT?
Exercise for adults with CMT
- Riding or rowing exercises, such as a stationary bike, tandem bike, recumbent bike, elliptical machine, or rowing machine.
- Swimming.
- Water aerobics.
- Vigorous gardening with components such as digging and lifting.
- Household chores, such as laundry, sweeping, and putting groceries away.