Can metformin cause gestational diabetes?
Can metformin cause gestational diabetes?
Meta-analysis has shown that metformin treatment during pregnancy could reduce the incidence of GDM in pregnant women with PCOS (92); however, another meta-analysis including 11 studies showed that metformin treatment in pregnant women with PCOS had no effect on the incidence of GDM in this population (93).
What are the side effects of taking metformin while pregnant?
It is important to be on the lowest effective dose to help reduce or prevent side effects with metformin. Metformin can also reduce the blood sugar too much, causing hypoglycemia….The most common side effects of metformin are:
- gas.
- heartburn.
- diarrhea.
- stomach pain.
- nausea.
- gastrointestinal changes.
Is metformin safe during pregnancy for gestational diabetes?
Metformin has been tested in clinical studies and is safe to take for gestational diabetes. Metformin helps keep both your weight gain and blood pressure down.
What causes gestational diabetes in pregnancy?
During pregnancy, your placenta makes hormones that cause glucose to build up in your blood. Usually, your pancreas can send out enough insulin to handle it. But if your body can’t make enough insulin or stops using insulin as it should, your blood sugar levels rise, and you get gestational diabetes.
Does metformin affect baby?
Metformin has a very low risk of birth defects and complications for your baby, making this drug safe to take before and during pregnancy. Metformin is also safe to take while breastfeeding your child.
What are the side effects of metformin?
Nausea, vomiting, stomach upset, diarrhea, weakness, or a metallic taste in the mouth may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. If stomach symptoms return later (after taking the same dose for several days or weeks), tell your doctor right away.
Should metformin be stopped during pregnancy?
Studies suggest that women using metformin during the second trimester for the treatment of gestational diabetes are not expected to have higher chances of pregnancy complications. The use of metformin through delivery has been associated with a risk of hypoglycemia (low blood sugar) in the baby.
How successful is metformin pregnancy?
Metformin has been evaluated in several studies in the context of PCOS pregnancy. It has been reported an 18.7% incidence of miscarriage in non-treated PCOS women, 10% in women who received metformin up to 32 weeks of gestation, and 0% in those who received metformin throughout pregnancy (p < 0.006) (Nawaz et al.
Is gestational diabetes my fault?
IT IS NOT YOUR FAULT! This is due to the hormones released from the placenta. Those who are not diabetic are able to increase insulin production sufficiently enough. Those who cannot increase insulin production enough, or cannot use the insulin that is there effectively enough, are diagnosed with gestational diabetes.
Can you have a healthy baby with gestational diabetes?
Pregnant people who have gestational diabetes can and do have healthy pregnancies and healthy babies. Most pregnant people get a test for gestational diabetes at 24 to 28 weeks of pregnancy. If untreated, gestational diabetes can cause problems for your baby, such as premature birth and stillbirth.
When should I stop taking metformin during pregnancy?
ANSWER. Despite the traditional response that all oral hypoglycemic agents are absolutely contraindicated during pregnancy,1-3 evidence that metformin is probably safe during the first trimester of pregnancy and beyond is accumulating.
Is metformin or insulin better during pregnancy?
A systematic review and meta-analysis revealed that metformin is better than insulin in reducing both, maternal weight gain during pregnancy and the frequency of PIH, with no changes in the frequency of hypoglycemia and preeclampsia (Gui et al., 2013).