What is atypical lentiginous melanocytic hyperplasia?
What is atypical lentiginous melanocytic hyperplasia?
2. Histologically, atypical lentiginous nevus is characterized by irregular lentiginous epidermal hyperplasia, the presence of nests in the rete ridges, predominance of isolated melanocytes in the basal layer of the epidermis, foci of moderate cellular atypia, and the absence of dermal nests.
What does Lentiginous spread mean?
In this type of melanoma, the word “acral” refers to the occurrence of the melanoma on the palms or soles. The word “lentiginous” means that the spot of melanoma is much darker than the surrounding skin. It also has a sharp border between the dark skin and the lighter skin around it.
Is lentiginous nevus cancerous?
Background: Atypical lentiginous nevus (of the elderly) is a peculiar form of dysplastic nevus. Clinically, this condition can resemble malignant melanoma and histologically, it has a lentiginous pattern with variable degrees of atypia and an absence of dermal nests.
What does lentiginous nevus mean?
Speckled lentiginous nevus is a patch of hyperpigmentation that can be seen on any area of the body. This patch contains a variable number of darkly pigmented macules and papules. Some authorities believe that speckled lentiginous nevus is a subtype of congenital melanocytic nevus.
Does melanocytic mean melanoma?
Melanocytes: These are the cells that can become melanoma. They normally make a brown pigment called melanin, which gives the skin its tan or brown color.
Is atypical melanocytic proliferation serious?
Atypical melanocytic lesions are also known as dysplastic nevus or dysplastic mole, atypical mole, or atypical melanocytic hyperplasia. Mole and nevus are synonymous. By definition these lesions are benign.
What is Lentiginous hyperplasia?
The term ‘atypical lentiginous hyperplasia’ is being increasingly used by pathologists to describe lentiginous hyperplasia where melanocytes display some cytological atypia with minimal nesting of melanocytes and without florid pagetoid spread.
What does Lentiginous mean?
freckled
Definitions of lentiginous. adjective. relating to or covered with or resembling freckles. synonyms: freckled, lentiginose patterned. having patterns (especially colorful patterns)
Can dysplastic nevus become melanoma?
A dysplastic nevus may develop into melanoma (a type of skin cancer), and the more dysplastic nevi a person has, the higher the risk of melanoma. A dysplastic nevus is sometimes called an atypical mole.
What are the warning signs of melanoma?
Other melanoma warning signs may include: Pigment, redness or swelling that spreads outside the border of a spot to the surrounding skin. Itchiness, tenderness or pain. Changes in texture, or scales, oozing or bleeding from an existing mole. Blurry vision or partial loss of sight, or dark spots in the iris.
What does Stage 1 melanoma look like?
Stage IA Melanoma: The melanoma tumor is less than 1.0 millimeter thick (less than the size of a sharpened pencil point) with or without ulceration (broken skin) when viewed under the microscope. Stage IB Melanoma: The melanoma tumor is more than 1.0 millimeter and less than 2.0 millimeters thick without ulceration.
What does melanocytic atypia mean?
Diagnosis And Treatment Atypical melanocytic lesions are pigmented moles that have abnormal cells under a microscope. These lesions will need to be evaluated by excision (removal) and evaluation by a dermatopathologist in a laboratory setting.