What does K C O mean?
What does K C O mean?
Carbon monoxide transfer coefficient (often abbreviated as KCO) is a parameter often performed as part of pulmonary function tests. It is also often written as DLCO/VA (diffusing capacity per liter of lung volume) and is an index of the efficiency of alveolar transfer of carbon monoxide.
What is KCO in spirometry?
KCO – The carbon monoxide transfer coefficient (KCO is approximately kCO/barometric pressure in mL/minute/ mmHg/L) is often written as DLCO/VA. It is an index of the efficiency of alveolar transfer of carbon monoxide.
What is a normal KCO?
The normal values for KCO are dependent on age and sex. A fit young adult may have a KCO of approximately 1.75 mmol/min/kPa/litre, an elderly adult may be about 1.25. This parameter is useful in the interpretation of a reduced transfer factor.
What causes high KCO?
Increased KCO occurs with (1) failure to expand normal lungs to predicted full inflation (extrapulmonary restriction); or (2) increased capillary volume and flow, either globally (left-to- right intracardiac shunting) or from flow and volume diversion from lost or damaged units to surviving normal units (e.g..
What does a high KCO mean?
a high KCO indicates a predominance of VC over VA due to. incomplete alveolar expansion but preserved gas exchange i.e. extra-parenchymal restriction such as pleural, chest wall or neuromuscular disease)
What is the difference between DLCO and KCO?
DLCO is a conductance, that is, the inverse of the resistance to the flow of CO molecules from air to blood. VA is required in the DLCO equation to quantify the flow of CO molecules across the alveolar capillary membrane. KCO is the logarithmic rate of decay of the alveolar CO concentration per unit of pressure.
What does high KCO mean?
What causes low KCO?
Decreased Kco, considered to reflect qualitative impairment of the alveolar-capillary membrane, is associated with conditions of diffuse alveolar-capillary disease (e.g. idiopathic pulmonary fibrosis, IPF), reduced alveolar surface or capillary density (e.g. emphysema, pulmonary hypertension, PH), or diminished …
What is DLCO and KCO?
What is the difference between DLCO and kCO?
How is kCO calculated?
The rate of disappearance of CO from alveolar gas during breath-holding = kCO (units: min-1) kCO is calculated as loge [CO0/COt]/BHT where CO0 and COt are the alveolar CO concentrations at the beginning and end of the breath-holding time (BHT).
How do you measure KCO?