Questions

Is Zosyn a strong antibiotic?

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Is Zosyn a strong antibiotic?

Is Zosyn (piperacillin / tazobactam) a broad spectrum antibiotic? Yes. Zosyn (piperacillin / tazobactam) is a broad spectrum antibiotic, which means that it works against many types of bacteria. This is why it is often used for people who are very sick or have serious infections.

What should I monitor before giving Zosyn?

Monitor the patient’s full blood count and kidney function. To ensure that the piperacillin-tazobactam (Zosyn) did not cause any anemia, leukopenia, or thrombocytopenia, as well as damage to the kidney function. Monitor the patient for any signs of bleeding such as bruising.

How long does IV Zosyn stay in your system?

Tazobactam is metabolized to a single metabolite that lacks pharmacological and antibacterial activities. Following single or multiple ZOSYN doses to healthy subjects, the plasma half-life of piperacillin and of tazobactam ranged from 0.7 to 1.2 hours and was unaffected by dose or duration of infusion.

What do you monitor Zosyn with?

Zosyn may cause serious side effects including:

  • severe stomach pain,
  • diarrhea that is watery or bloody (occurring months after the last dose),
  • convulsions (seizures),
  • fever,
  • mouth sores,
  • skin sores,
  • sore throat,
  • cough,

Does Zosyn make you tired?

Nausea, constipation, diarrhea, headache, or trouble sleeping may occur.

Is Zosyn hard on kidneys?

If alternative treatment options are inadequate or unavailable, monitor renal function during treatment with Zosyn. Precautions section stating that combined use of these two drugs may be associated with an increased incidence of acute kidney injury.

Why is Zosyn given over 4 hours?

Summary: EI β-lactam therapy is now considered a key aspect of antimicrobial stewardship, and published evidence indicates that i.v. infusion of piperacillin-tazobactam over extended periods (e.g., four hours) instead of the traditionally recommended 30 minutes may offer several advantages, including reduced mortality …

What does Zosyn do in the body?

Zosyn contains a combination of piperacillin and tazobactam. Piperacillin and tazobactam are penicillin antibiotics that fight bacteria in the body. Zosyn is used to treat many different infections caused by bacteria, such as stomach infections, skin infections, pneumonia, and severe uterine infections.

Can Zosyn cause confusion?

Tell your doctor if you have serious side effects of Zosyn including muscle cramps or spasms, swelling of the arms/legs/hands/feet, easy bruising or bleeding, chest pain, confusion, new signs of infection (such as fever, persistent sore throat), severe abdominal or stomach pain, slow/fast/irregular heartbeat.

What kind of bacteria does zosyn treat?

Piperacillin/tazobactam (Zosyn) It covers Streptococci, Staphylococci (but not methicillin-resistant S. aureus [MRSA]), Hemophilus, Moraxella, Enterobacteriaceae, and Pseudomonas aeruginosa. [5],[6] It is an excellent anti-anaerobic agent, but does not treat clostridium difficile infections.

Can zosyn increase creatinine?

Piperacillin-tazobactam may increase serum creatinine due to a reduction in tubular creatinine secretion, caused by inhibition of the organic anion transporter. This causes “pseudo-nephrotoxicity” – increase serum creatinine, without impaired renal function or true renal injury.

Is zosyn used for pneumonia?

Piperacillin and tazobactam is a combination penicillin antibiotic that is used to treat many different infections caused by bacteria, such as stomach infections, skin infections, pneumonia, and severe uterine infections.