What is an IFE blood test for?
What is an IFE blood test for?
This test is most often used to help diagnose or monitor a variety of different conditions. These include: Multiple myeloma, a cancer of the white blood cells. Other forms of cancer, such as lymphoma (cancer of the immune system) or leukemia (cancer of blood-forming tissues, such as bone marrow)
What is Ife interpretation mean?
Immunofixation electrophoresis (IFE) is a qualitative technique that provides a detailed separation of individual immunoglobulins according to their electrical charges followed by the application of specific antiserum (anti-IgM, anti kappa, etc.) and a stain, to help visualize the patterns.
Is Ife the same as SPEP?
IFE is performed after the specimen is subjected to electrophoresis in the same process as SPEP but in multiple lanes.
What is urine IFE?
Urine immunofixation is a test that measures proteins in your urine. It specifically looks for monoclonal protein, or M-protein, which shouldn’t be there in most cases. Doctors will be able to find out if you have conditions such as multiple myeloma or primary amyloidosis through urine immunofixation.
Why would a doctor order an immunofixation test?
The immunofixation blood test is used to identify proteins called immunoglobulins in blood. Too much of the same immunoglobulin is usually due to different types of blood cancer. Immunoglobulins are antibodies that help your body fight infection.
What does a positive immunofixation mean?
Positive results from the test indicate the presence of abnormal Ig. This may suggest the existence of an underlying health condition, such as: an immune system disorder. multiple myeloma. Waldenstrom’s macroglobulinemia.
What is SPEP with reflex IFE?
Clinical Significance Protein Electrophoresis, with Total Protein and Reflex to IFE, Serum – Serum protein electrophoresis (SPE) is an analytical technique that provides separation of serum protein into six fractions: Albumin, Alpha-1, Alpha-2, Beta-1, Beta-2, and Gamma.
What does an abnormal immunofixation mean?
An abnormal result may be due to: Amyloidosis (buildup of abnormal proteins in tissues and organs) Leukemia or Waldenström macroglobulinemia (types of white blood cell cancers) Lymphoma (cancer of the lymph tissue) Monoclonal gammopathy of unknown significance (MGUS)
What is normal for protein in urine?
Normally, you should have less than 150 milligrams (about 3 percent of a teaspoon) of protein in the urine per day. Having more than 150 milligrams per day is called proteinuria.
Can protein in urine be cured?
Can proteinuria be prevented? Proteinuria cannot be prevented, but it can be controlled. Many of the causes of proteinuria can be treated (diabetes, high blood pressure, preeclampsia and kidney disease), allowing your healthcare provider to improve the condition.